Common allergens include penicillin, latex, aspirin,strawberries, shellfish, and peanuts. Histamine, released by mast cells, produces virtually all the clinical signs and symptoms associated with allergic reactions, including rash, bronchospasm, and vasodilation.
The severity of the allergic reaction depends on how rapidly and where these chemicals are released. Delayed-onset allergies most commonly involve only the skin and are not life-threatening. Immediate-onset allergies are life-threatening, usually involving the respiratory and cardiovascular systems and producing bronchospasm and a drop in blood pressure. This requires immediate emergency management to keep the person alive.
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